Tartaric Acid Click to View Image C4H6O6 150.09
Butanedioic acid,2,3-dihydroxy-;Butanedioic acid,2,3-dihydroxy-,[R-(R*,R*)]-.
Tartaric acid;L-(+)-Tartaric acid [526-83-0]and [87-69-4]. »Tartaric Acid,dried over phosphorus pentoxide for 3hours,contains not less than 99.7percent and not more than 100.5percent of C4H6O6. Packaging and storage— Preserve in well-closed containers. Identification— A: It responds to the tests for Tartrate á191ñ. B: When ignited,it gradually decomposes,emitting an odor resembling that of burning sugar (distinction from citric acid). Specific rotation á781Sñ: between +12.0and +13.0. Test solution: 200mg per mL,in water. Loss on drying á731ñ Dry it over phosphorus pentoxide for 3hours:it loses not more than 0.5%of its weight. Residue on ignition á281ñ: not more than 0.1%. Limit of oxalate— Nearly neutralize 10mLof a solution of it (1in 10)with 6Nammonium hydroxide,and add 10mLof calcium sulfate TS:no turbidity is produced. Sulfate á221ñ To 10mLof a solution (1in 100)add 3drops of hydrochloric acid and 1mLof barium chloride TS:no turbidity is produced. Heavy metals,Method IIá231ñ: 0.001%. Organic volatile impurities,Method Iá467ñ: meets the requirements. Assay— Place about 2g of Tartaric Acid,previously dried and accurately weighed,in a conical flask.Dissolve it in 40mLof water,add phenolphthalein TS,and titrate with 1Nsodium hydroxide VS.Each mLof 1Nsodium hydroxide is equivalent to 75.04mg of C4H6O6. Auxiliary Information— Staff Liaison:Catherine Sheehan,B.Sc.,Scientist Expert Committee:(EMC)Excipients:Monograph Content USP28–NF23Page 3097 Phone Number:1-301-816-8262