Tolu Balsam Syrup »Prepare Tolu Balsam Syrup as follows (seePharmaceutical Compounding—Nonsterile Preparations á795ñ). Tolu Balsam Tincture 50mL Magnesium Carbonate 10g Sucrose 820g Purified Water,a sufficient quantity,
to make 1000mL Add the Tincture all at once to the Magnesium Carbonate and 60g of the Sucrose in a mortar,and mix.Gradually add 430mLof Purified Water with trituration,and filter.Dissolve the remainder of the Sucrose in the clear filtrate with gentle heating,strain the syrup while warm,and add sufficient Purified Water through the strainer to make the product measure 1000mL,and mix. NOTE—Tolu Balsam Syrup may also be prepared as follows.Place 760g of the Sucrose in a suitable percolator,the neck of which is nearly filled with loosely packed cotton,moistened after packing with a few drops of water.Pour the filtrate,obtained as directed in the preceding instructions,on the Sucrose,and regulate the outflow to a steady drip of percolate.When all of the liquid has run through,return portions of the percolate,if necessary,to dissolve all the Sucrose.Then pass enough Purified Water through the cotton to make the product measure 1000mL,and mix.
Packaging and storage— Preserve in tight containers,and store at controlled room temperature. Labeling— The label states the Latin binomial name and,following the official name,the part of the plant source from which the article was derived. Acid value— Take 2%of solution,add phenolphthalein TS,and titrate with 0.5Nalcoholic potassium hydroxide VS:the acid value is between 112and 168. Alcohol content,Method IIá611ñ: between 3.0%and 5.0%of C2H5OH. Auxiliary Information— Staff Liaison:Claudia C.Okeke,Ph.D.,Associate Director Expert Committee:(CRX)Compounding Pharmacy USP28–NF23Page 3099 Pharmacopeial Forum:Volume No.28(5)Page 1467 Phone Number:1-301-816-8243